{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"On Gene Variances","description":"Dr. Pastore and Lexie cover how certain variations of specific genes can affect your performance, your nutrition, your cravings and even how food tastes.   In-depth topics include how genetics affect: High carbohydrate consumption and low HDL cholesterol levels How food tastes, and why some people can never get enough sugar How your risk for tendon\/ligament\/joint injury is increased\/decreased Over-eating and difficulty losing weight       Genetic SNPs covered in the episode:   KCTD10-GG MMAB-GG MVK May cause low HDL (\u201cgood\u201d) cholesterol levels with high carbohydrate consumption (~231g+ per day)   SLC2A2 rs5400 - T allele (even just one) \u201cSweet tooth\u201d gene, linked to over-eating, not feeling satisfied after sugar consumption, less sensitive to feeling the affects of high glucose levels in blood   TAS1R3-AA TAS1R3-GA Sugar tastes less sweet, increases the likelihood over overconsumption of sugar and artificial sweeteners   TAS2R38-C allele TAS2R38-G allele Do not like the taste of bitter foods (coffee, broccoli, kale, Brussels sprouts), over-salt or sweeten foods to cover up the taste   TAS2R38-TT Find bitter foods less bitter than other people (enjoy broccoli, cabbage, kale, etc)   COL5A1-TT Decreased elasticity and range of motion in joints. Increased risk of injuring joints, connective tissue (tendons\/ligaments) and soft tissue.   COL5A1-CC Protective genotype, reduced rate of tendon injury   COL1A1-TT Decreased risk of injuring joints, connective tissue (tendons\/ligaments) and soft tissue.   GDF5-T allele Increased risk for joint injuries, can be a warning sign of early (mid-40\u2019s) onset osteoarthritis   MC4R-C allele KCDT15-C allele Increases likelihood of higher BMI (from fat mass), slows the process of weight loss, can cause more cravings for higher caloric\/processed food intake   COMT-GG Increases the likelihood to overeat   SHTB2, LEP, PCSK1-2, and FTO are currently being researched for their connection to obesity. ","author_name":"The Pastore Podcast","author_url":"https:\/\/drrobertpastore.com\/","html":"