{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"Episode 903: Treating Precipitated Opioid Withdrawal","description":"Contributor: Aaron Lessen MD Educational Pearls:   Opioid overdoses that are reversed with naloxone (Narcan), a mu-opioid antagonist, can precipitate acute withdrawal in some patients   Treatment of opioid use disorder with buprenorphine can also precipitate withdrawal   Opioid withdrawal symptoms include nausea, vomiting, diarrhea, and agitation   Buprenorphine works as a partial agonist at mu-opioid receptors, which may alleviate withdrawal symptoms    The preferred dose of buprenorphine is 16 mg    Treatment of buprenorphine-induced opioid withdrawal is additional buprenorphine   Adjunctive treatments may be used for other opioid withdrawal symptoms    Nausea with ondansetron   Diarrhea with loperamide   Agitation with hydroxyzine    References 1. Quattlebaum THN, Kiyokawa M, Murata KA. A case of buprenorphine-precipitated withdrawal managed with high-dose buprenorphine. Fam Pract. 2022;39(2):292-294. doi:10.1093\/fampra\/cmab073 2. Spadaro A, Long B, Koyfman A, Perrone J. Buprenorphine precipitated opioid withdrawal: Prevention and management in the ED setting. Am J Emerg Med. 2022;58:22-26. doi:10.1016\/j.ajem.2022.05.013 Summarized by Jorge Chalit, OMSII | Edited by Meg Joyce &amp;amp; Jorge Chalit &amp;nbsp; ","author_name":"Emergency Medical Minute","author_url":"https:\/\/www.emergencymedicalminute.com","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/31256912\/height\/90\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/fa102a\/\" height=\"90\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/item\/31256912"}