{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":300,"width":600,"title":" \ud83e\uddec One Mutation, Massive Risk: EGFR T790M and Inherited Lung Cancer","description":"\ud83e\uddec Rare Variant, Real Risk: EGFR T790M and Lung Cancer Can lung cancer risk be inherited\u2014even in never-smokers? \ud83e\udec1\ud83d\udead In &amp;gt;3.3 million individuals, germline EGFR T790M was rare (~1 in 15,850) but strongly associated with lung cancer (OR 25.18). The association was particularly striking among never-smokers, and the variant showed remarkable lung-cancer specificity. A Southern Appalachian founder effect also revealed how genes, geography &amp;amp; history can converge on modern disease risk. \ud83d\uddfa\ufe0f\ud83e\uddec \ud83d\udca1 A compelling case for refining genetic risk assessment and future targeted screening strategies. ","author_name":"Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity!","author_url":"http:\/\/www.MasterMedFacts.com","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/42965473\/height\/300\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"300\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/206468148"}