{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":300,"width":600,"title":"\ud83e\udec0 The Heart\u2019s Forgotten Drain: Aging, Lymphatics &amp; Inflammation","description":"\ud83e\udec0 Could the aging heart have a drainage problem? A fascinating study in Nature Cardiovascular Research shows that aging reduces cardiac lymphatic vessels, with tighter junctions, impaired clearance, inflammation, edema, fibrinogen and amyloid accumulation. \ud83d\udd25 \ud83e\uddec Mechanistically: aging \u2192 \u2193VEGFC \u2192 \u2191nuclear IL-33 \u2192 lymphatic endothelial cell loss\/remodeling. \ud83c\udfaf IL-33 silencing or VEGFC restoration rescued lymphatic density and reduced inflammation\u2014but VEGFC did not reverse established diastolic dysfunction. \ud83d\udca1 Perhaps cardiac aging is not only about blood vessels. Lymphatics matter ","author_name":"Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity!","author_url":"http:\/\/www.MasterMedFacts.com","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/42923287\/height\/300\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"300\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/206337247"}