{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"In the Lab with Dr. Lucas Sullivan: let cancer eat cake","description":"Dr. Lucas Sullivan, a cancer metabolism expert at Fred Hutch Cancer Center talks with John Higgins about a new study showing that cancers driven by a specific mutation crave a nutrient so much that eating too much of it can be lethal. Healthy cells aren\u2019t prone to stuffing themselves with this nutrient. That difference presents an opportunity for precision oncology: we can supplement a patient\u2019s diet to force-feed tumors the nutrient while sparing healthy cells.   Key takeaways:  A recent study by Dr. Lucas Sullivan, a cancer metabolism expert, finds that feeding NRF2-mutated tumors too much of a nutrient they crave makes them vulnerable to slower growth and cell death. NRF2 genetic mutations are common in lung cancers but also appear in several other cancers. Force-feeding NRF2-mutated tumors the nutrient they crave could kill the cancerous cells while sparing the healthy ones, a prime example of precision oncology. ","author_name":"Bench to Bedside and Beyond","author_url":"https:\/\/sites.libsyn.com\/591875","html":"