{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":300,"width":600,"title":"\u2764\ufe0f\u200d\ud83d\udd25\ud83c\udfc3 Sleep, Exercise, Immunity: How Lifestyle Rewrites Clonal Haematopoiesis","description":"\ud83e\uddec\ud83d\udca4\ud83c\udfc3\u200d\u2642\ufe0f Can lifestyle modify the cardiovascular risk associated with clonal haematopoiesis (CH)? &amp;nbsp; In this elegant Nature study, investigators demonstrate that sleep and exercise exert mutation-specific effects on CH. Moderate-to-vigorous physical activity was associated with lower prevalence of non-DNMT3A CH in large human cohorts, while mechanistic studies revealed that uninterrupted sleep and exercise can suppress JAK2V617F- and TET2-driven clonal expansion and reduce atherosclerosis. \ud83d\udd2c\u2764\ufe0f &amp;nbsp; The message is clear: lifestyle is not merely preventive\u2014it may selectively reprogram mutant cells and reshape cardiovascular risk. #Cardiology #PrecisionMedicine #CHIP #Atherosclerosis #MedicalPodcasts \ud83e\uddec\ud83d\udee1\ufe0f ","author_name":"Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity!","author_url":"http:\/\/www.MasterMedFacts.com","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/41635525\/height\/300\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"300\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/202940745"}