{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"Terrific Tocotrienols with Dr. Barrie Tan | Rational Wellness Podcast 462","description":"Dr. Barrie Tan on Tocotrienols: Annatto Vitamin E, Lipid Antioxidant Protection, and Clinical Uses   Dr. Ben Weitz hosts Dr. Barrie Tan to discuss tocotrienols, lesser-known vitamin E family members (eight total: four tocopherols and four tocotrienols) that differ from common alpha-tocopherol-only supplements. Tan describes discovering tocotrienols in annatto in South America, noting annatto is uniquely tocopherol-free and rich in delta and gamma tocotrienols. He argues alpha-tocopherol is only clearly tied to bringing a fetus to full term and that excess alpha-tocopherol can antagonize tocotrienol absorption and clinical results. Tan emphasizes tocotrienols as superior lipid antioxidants that protect cell-membrane phospholipids and help stabilize omega-3 oils, and reviews studies and proposed benefits across fatty liver disease, metabolic syndrome\/diabetes, dyslipidemia, inflammation markers, bone density in post-menopausal women and obesity, plaque-related endpoints, and selected cancers, plus discussion of radiation\/antioxidant concerns and dosing ranges used in trials. 00:00 Show Intro and Mission 00:59 Meet Dr Barrie Tan 03:12 Annatto Discovery Story 08:03 Tocotrienols vs Tocopherols 11:20 Lipid Antioxidant Explained 16:16 Omega 3 Protection Strategy 20:34 Alpha Tocopherol Antagonism 24:26 Clinical Wins and Conditions 25:53 Obesity Study Results 30:33 Cancer Research and Ferroptosis 31:40 Delta Gamma Standouts 32:10 Iron Overload Ferroptosis Link 33:57 Apollo Wearable Sponsor 35:27 Antioxidants During Cancer Therapy 38:05 Radiation Countermeasure Evidence 43:31 Cancer Dosage Guidance 45:35 Heart Metabolic Benefits 49:35 Statins CoQ10 GG Explained 54:28 Black Seed Oil Combo 55:47 Books Vitamin K Wrap Up 58:10 Podcast Closing Credits   Dr. Barrie Tan has a PhD in chemistry and he's spent his life dedicated to researching vitamin E, among other nutritional compounds. Dr. Tan was chief science officer for Designs For health from 2018 to 2025. He's currently senior advisor for Everwell health and he is credited with discovering tocotrienols in palm, rice, and annatto, with annatto being the most efficient source.    Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS\/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111. ","author_name":"Rational Wellness Podcast","author_url":"https:\/\/www.drweitz.com","html":"