{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"E 205 PEPTIDE PLAYBOOK \u2013 PART 5 Understanding How Aging Happens Studying Mitochondrial Dysfunction in Aging","description":"Welcome back to The Peptide Playbook! In this episode, I\u2019m joined by my colleague Dr. Robert Frankel, and we dive deep into one of the most exciting topics in anti-aging and wellness right now: mitochondrial health. We break down what mitochondria actually do (in a way that finally makes sense), why they\u2019re so critical for energy, aging, and disease\u2014and how peptides like NAD, MOTS-c, and SS-31 may help optimize how your body functions at a cellular level. One of the most fascinating parts? The concept of \u201cexercise in a bottle\u201d\u2014how certain peptides can mimic some of the metabolic benefits of working out by improving energy production, fat metabolism, and even muscle function. We also talk about:  Why energy deficiency is at the root of many health issues&amp;nbsp; What \u201czombie cells\u201d are and how they accelerate aging&amp;nbsp; The real role of free radicals (and why antioxidants alone aren\u2019t enough)&amp;nbsp; How to think about peptides safely and strategically&amp;nbsp;  This is a powerful, science-backed conversation\u2014but still approachable and practical. As always, this is for educational purposes only\u2014make sure to consult with a qualified professional before starting any treatment. 00:00:00 Intro \u2013 Welcome to The Peptide Playbook 00:01:10 Why This Topic Matters (Mitochondria &amp;amp; Aging) 00:03:30 What Are Mitochondria? (Simple Explanation) 00:07:20 Mitochondria and Energy (ATP Basics) 00:10:30 Why We Age: Mitochondrial Decline 00:13:40 The 3 Main Problems of Aging Cells 00:15:10 Energy Loss &amp;amp; Fatigue Explained 00:18:00 Zombie Cells (Senescent Cells) 00:23:40 Free Radicals &amp;amp; Oxidative Stress 00:28:30 What Damages Mitochondria? 00:32:00 How to Reverse Mitochondrial Dysfunction 00:34:20 NAD \u2013 The Foundation of Energy 00:41:30 Krebs Cycle &amp;amp; Cellular Energy Explained 00:45:50 Who Should Consider NAD? 00:48:20 MOTS-c \u2013 \u201cExercise in a Bottle\u201d &amp;nbsp;00:54:10 How MOTS-c Burns Fat &amp;amp; Builds Muscle 00:58:00 AMPK Pathway Explained Simply 01:00:30 SS-31 \u2013 Repairing Mitochria 01:04:20 How to Use These Peptides (Protocols) 01:07:10 Who Are Ideal Candidates? 01:10:20 GLP-1s, Hormones &amp;amp; Longevity 01:12:40 Future of Peptides &amp;amp; Medicine &amp;nbsp;01:14:10 Final Thoughts &amp;amp; Outro ","author_name":"Bathroom Diaries w. Dr Sofia Din","author_url":"https:\/\/botoxguru.org\/","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/41035525\/height\/90\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"90\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/201251495"}