{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"Immune Booster 28: Immunometabolism, Inflammation, and Building Biotechs with Luke O\u2019Neill","description":"Luke O\u2019Neill recounts his role in discovering key components of the TLR signaling pathway, explains how pursuing unexpected research questions keeps him motivated, and reflects on his experiences as an entrepreneur founding biotech companies. Host:&amp;nbsp;Cindy Leifer Guest:&amp;nbsp;Luke O\u2019Neill Subscribe (free): Apple Podcasts,&amp;nbsp;RSS,&amp;nbsp;email Become a&amp;nbsp;patron&amp;nbsp;of&amp;nbsp;Immune! Links for this episode  MicrobeTV Discord Server O\u2019Neill lab Identification of&amp;nbsp;MAL in the TLR signaling&amp;nbsp;pathway (Nature, 2001) GDF 15, immunometabolism&amp;nbsp;and anti-inflammatories (An Rev Pharmacol Tox, 2026) Itaconate and regulation&amp;nbsp;of inflammation (Nat Metab, 2024) Time stamps by&amp;nbsp;Jolene&amp;nbsp;Ramsey. Thanks!  Music by&amp;nbsp;Tatami. Logo image by&amp;nbsp;Blausen Medical  Send your immunology questions and comments to&amp;nbsp;immune@microbe.tv Information on this podcast should not be construed as medical advice. ","author_name":"Immune","author_url":"http:\/\/microbe.tv\/immune","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/41035165\/height\/90\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"90\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/item\/41035165"}