{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":300,"width":600,"title":"The Genetics of GLP-1 Response \ud83e\uddec\ud83d\udc8a\ud83d\udcca","description":"Why do GLP-1 therapies transform some patients\u2014and barely move the needle in others? \ud83e\uddec\ud83d\udc89 &amp;nbsp; A recent Nature study (~28,000 participants) identifies GLP1R and GIPR variants linked to both weight loss efficacy and GI side effects. &amp;nbsp; \ud83d\udcca Signal: modest for weight loss, stronger for tolerability \ud83e\udde0 Insight: genetics + clinical factors explain ~25% variability \ud83d\ude80 Implication: early steps toward precision obesity therapeutics &amp;nbsp; The future may not be \u201cone drug fits all,\u201d but one genome, one strategy. ","author_name":"Dr. RR Baliga's 'Podkast for the Kurious Doc'","author_url":"http:\/\/www.MasterMedFacts.com","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/40796650\/height\/300\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"300\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/200611015"}