{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":300,"width":600,"title":"Gut Bacteria, Inflammation, Brain Decline \ud83e\udde0\ud83e\udda0\u26a1","description":"\ud83e\udde0\ud83e\udda0 Microbes. Metabolites. Memory. &amp;nbsp; A fascinating new Nature study reveals a gut\u2013brain pathway driving age-related cognitive decline. &amp;nbsp; Expansion of Parabacteroides goldsteinii in aging microbiomes increases medium-chain fatty acids, activating GPR84 signaling in peripheral myeloid cells. The resulting inflammation suppresses vagal sensory signaling, blunting hippocampal neuronal activation and impairing memory. &amp;nbsp; Even more intriguing: interventions restoring gut\u2013brain communication improved cognition in mice. &amp;nbsp; This work highlights the gut microbiome as a therapeutic target for cognitive aging\u2014suggesting that microbiome modulation, vagal stimulation, or GPR84 inhibition may one day help protect memory. ","author_name":"Dr. RR Baliga's 'Podkast for the Kurious Doc'","author_url":"http:\/\/www.MasterMedFacts.com","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/40492240\/height\/300\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"300\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/199717240"}