{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"PANTHER-P2Y12 Inhibitor or Aspirin moNoTHERapy as Secondary Prevention in Patients with CAD","description":" he PANTHER&amp;nbsp;study&amp;nbsp;indicates&amp;nbsp;that clopidogrel provides superior protection against major cardiovascular events compared to aspirin in patients with coronary artery disease, without increasing bleeding risk. This supports its use in individuals at higher risk of gastrointestinal complications, reinforcing current clinical preferences. Overall, these results could inform long-term treatment strategies and improve outcomes for millions of patients worldwide.&amp;nbsp;    &amp;nbsp;   In this interview, Alison L. Bailey, MD, FACC and Prof. Marco&amp;nbsp;Valgimigli&amp;nbsp;discuss \u201cPANTHER-P2Y12 Inhibitor or Aspirin&amp;nbsp;moNoTHERapy&amp;nbsp;as Secondary Prevention in Patients with CAD\u201d.&amp;nbsp;    &amp;nbsp;   Suggested Materials:&amp;nbsp;   1.&amp;nbsp;Giacoppo D, Gragnano F, Watanabe H, et al.&amp;nbsp;P2Y12\u202finhibitor or aspirin after percutaneous coronary intervention: individual patient data meta-analysis of&amp;nbsp;randomised&amp;nbsp;clinical trials.\u202fBMJ. 2025;389:e082561.&amp;nbsp;Published&amp;nbsp;2025&amp;nbsp;Jun&amp;nbsp;4.&amp;nbsp;doi:10.1136\/bmj-2024-082561&amp;nbsp;   2.&amp;nbsp;Valgimigli M, Hong SJ, Gragnano F, et al.&amp;nbsp;De-escalation to ticagrelor monotherapy versus 12 months of dual antiplatelet therapy in patients with and without acute coronary syndromes: a systematic review and individual patient-level meta-analysis of&amp;nbsp;randomised&amp;nbsp;trials.\u202fLancet. 2024;404(10456):937-948. doi:10.1016\/S0140-6736(24)01616-7&amp;nbsp;   3.&amp;nbsp;P2Y(12) Inhibitor or Aspirin Monotherapy for Secondary Prevention of Coronary Events. Gragnano F, Cao D,&amp;nbsp;Pirondini&amp;nbsp;L, Franzone A, Kim HS, von Scheidt M, Pettersen AR, Zhao Q, Woodward M,&amp;nbsp;Chiarito M, McFadden EP, Park KW, Kastrati A,&amp;nbsp;Seljeflot&amp;nbsp;I, Zhu Y, Windecker S, Kang J,&amp;nbsp;Schunkert&amp;nbsp;H, Arnesen H, Bhatt DL, Steg PG,&amp;nbsp;Calabr\u00f2&amp;nbsp;P, Pocock S, Mehran R,&amp;nbsp;Valgimigli&amp;nbsp;M; PANTHER Collaboration. J Am Coll&amp;nbsp;Cardiol. 2023;82(2):89-105.&amp;nbsp;doi: 10.1016\/j.jacc.2023.04.051&amp;nbsp;   Subscribe on Apple&amp;nbsp;Podcasts&amp;nbsp;|&amp;nbsp;Subscribe to ACCEL&amp;nbsp;  ","author_name":"ACCEL Lite: Featured ACCEL Interviews on Exciting CV Research","author_url":"http:\/\/accelaccorg.libsyn.com\/website","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/39327660\/height\/90\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"90\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/196336140"}