{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"Jerry Avorn: Countering the Drug Marketing Machine","description":"Howie and Harlan are joined by Harvard internist Jerry Avorn to discuss his research on the pharmaceutical industry and his work promoting evidence-based prescribing. Harlan highlights new results from the American Heart Association meeting, including a one-time CRISPR-based therapy for high cholesterol; Howie reports on an outbreak of infant botulism. Show notes: Research from the American Heart Association Meeting \u201cPhase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3\u201d  \u201cFirst-in-human trial of CRISPR gene-editing therapy safely lowered cholesterol, triglycerides\u201d  \u201cCardiac Allograft Vasculopathy Inhibition with Alirocumab: The CAVIAR Trial\u201d  \u201cPCSK9 medication plus statin may help lower cholesterol after heart transplant\u201d  \u201cInvestigational daily pill lowered bad cholesterol as much as injectables\u201d Jerry Avorn  Science Direct: Academic Detailing Jerry Avorn: \u201cPrinciples of Educational Outreach ('Academic Detailing') to Improve Clinical Decision Making\u201d Alosa Health  FDA: Accelerated Approval Jerry Avorn: Rethinking Medications: Truth, Power, and the Drugs You Take  FDA: Direct-to-Consumer (DTC) Advertisements H.R.5952 - Prescription Drug User Fee Act of 1992 FDA: FY 2025 FDA Budget Summary Centers for Medicare &amp;amp; Medicaid Services: Open Payments&amp;nbsp; H.R.3590 - Patient Protection and Affordable Care Act \u201cAducanumab Discontinued as an Alzheimer's Treatment\u201d  FDA: ELEVIDYS Brigham and Women\u2019s Hospital &amp;amp; Harvard Medical School: Division of Pharmacoepidemiology and Pharmacoeconomics Amazon.com: Featured comments on Rethinking Medications Infant Botulism  California Department of Public Health: \u201cOutbreak of Infant Botulism Linked to ByHeart Infant Formula\u201d  California Department of Public Health: Infant Botulism Treatment and Prevention Program  CDC: \u201cInfant Botulism Outbreak Linked to Infant Formula, November 2025\u201d  \u201cByHeart recalls all baby formula sold nationwide as infant botulism outbreak grows\u201d California Department of Public Health: What is BabyBIG?  California Department of Public Health: Postponement of BabyBIG Fee Increase  California Department Of Public Health: Invoice and Purchase Agreement for BabyBIG  In the Yale School of Management\u2019s MBA for Executives program, you\u2019ll get a full MBA education in 22 months while applying new skills to your organization in real time. Yale's  Executive Master of Public Health offers a rigorous public health education for working professionals, with the flexibility of evening online classes alongside three on-campus trainings. Email Howie and Harlan comments or questions. &amp;nbsp; ","author_name":"Health &amp; Veritas","author_url":"https:\/\/insights.som.yale.edu\/podcasts\/health-veritas","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/39020780\/height\/90\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"90\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/195417490"}