{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"Gene Therapy\u2019s Dark Ages","description":"Gene therapy is based on a simple-sounding, yet deceptively complicated premise: adding or replacing faulty genes to fix medical problems. A compelling idea that came out of breakthroughs in DNA research, the field grew lightning fast. But the death of teenager Jesse Gelsinger after a gene therapy clinical trial left the public and scientists questioning the field\u2019s promise.&amp;nbsp; Why did researchers push ahead with clinical trials despite gene therapy still being&amp;nbsp; in its infancy? What does the Jesse Gelsinger story tell us about the personal risk behind medical breakthroughs? Credits Host:&amp;nbsp;Alexis Pedrick Executive Producer:&amp;nbsp;Mariel Carr Producer:&amp;nbsp;Rigoberto Hernandez Associate Producer: Sarah Kaplan Audio Engineer:&amp;nbsp;Samia Bouzid Music&amp;nbsp;by&amp;nbsp;Blue Dot Sessions Resource List  American Experience: The Boy in the Bubble. PBS. Begley, Sharon. \u201cOut of Prison, the \u2018Father of Gene Therapy\u2019 Faces a Harsh Reality: a Tarnished Legacy and an Ankle Monitor.\u201d STAT News, July 23, 2018. Cobb, Matthew. As Gods: A Moral History of the Genetic Age. New York: Basic Books, 2022. \u201cC\u2011SPAN: Paul Gelsinger.\u201d C\u2011SPAN.  Gelsinger, Paul L. \u201cJesse\u2019s Intent.\u201d Circare. ABC Evening News. Vanderbilt Television News Archive, December 8, 1999. CBS Evening News. Vanderbilt Television News Archive, May 28, 1999. NBC Nightly News Broadcast. Vanderbilt Television News Archive, December 8, 1999. \u201cReport and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy.\u201d Georgetown University Library. Rinde, Meir. \u201cThe Death of Jesse Gelsinger, 20 Years Later.\u201d Science History Institute, June 4, 2019. Stolberg, Sheryl Gay. \u201cThe Biotech Death of Jesse Gelsinger.\u201d New York Times Magazine, November 28, 1999. \u201cTeen Dies Undergoing Experimental Gene Therapy.\u201d Washington Post, September 29, 1999. \u201cThe Glimmering Promise of Gene Therapy.\u201d MIT Technology Review, November 1, 2006. The NewsHour with Jim Lehrer, 1999-12-08. NewsHour Productions. American Archive of Public Broadcasting (GBH and the Library of Congress), Boston, MA and Washington, DC. Wilson, James . \u201cLessons learned from the gene therapy trial for ornithine transcarbamylase deficiency.\u201d ","author_name":"Distillations | Science History Institute","author_url":"https:\/\/www.sciencehistory.org\/stories\/distillations-pod\/","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/37823230\/height\/90\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"90\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/191917380"}