{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"The Hidden Heart Benefits of GLP-1s (with Dr. Ralph DeFronzo)","description":"In this breakthrough episode, Dr. Ralph DeFronzo\u2014one of the most respected names in metabolic health\u2014joins Elizabeth to discuss the real story behind GLP-1 medications. If you\u2019ve ever wondered: Do I have to stay on GLP-1s forever? Are lower doses (or \u201cmicrodoses\u201d) actually effective? Can I activate GLP-1 naturally\u2014without prescriptions? Is it really safe for long-term use? \u2026this episode gives you honest answers, straight from an expert who helped define modern diabetes treatment. Dr. D explains how GLP-1s not only facilitate weight loss by reducing one\u2019s appetite, but also protect your heart, liver, brain and kidneys\u2014and why most people overlook this crucial benefit. You\u2019ll learn what makes someone a \u201csuper responder,\u201d the link between cortisol and weight loss resistance, and how to finally quiet \u201cFood Noise\u201d for good. \u2728 &amp;nbsp; *** CLICK HERE TO GET ==&amp;gt; &amp;nbsp;FREE &quot;Freedom From Food Noise&quot; Masterclass: https:\/\/go.elizabethmcgann.com\/start *** &amp;nbsp; SHOW NOTES: [ 00:00 ] Introduction [ 01:45 ] GLP-1s: Not just for weight loss\u2014they also protect your heart, liver, kidneys &amp;amp; brain [ 03:40 ] People often forget: GLP-1s were originally created to treat diabetes [ 07:35 ] &amp;nbsp;Are low doses (aka \u201cmicrodosing\u201d) effective? DeFronzo\u2019s take on trending wellness practices [ 10:55 ] Significant benefits of GLP-1s for non-diabetics [ 13:25 ] How much weight do you really need to lose to help your heart? The 10% threshold explained [ 15:55 ] \u201cWeighted\u201d Question: Once on them, do you need to be on GLP-1s forever? The real answer from an expert who knows [ 19:30 ] Why diet and exercise alone don\u2019t work long-term for most people\u2014and what actually does work [ 22:30 ] Can you \u201creverse\u201d diabetes or insulin resistance naturally? The symptoms, YES... but it\u2019s complicated! [ 25:00 ] How GLP-1s reduce inflammation and rewire your metabolism at the cellular level [ 28:00 ] The truth about \u201cnatural\u201d GLP-1 boosters like berberine, fiber and protein [ 31:00 ] Dr. DeFronzo\u2019s surprising eating habit\u2014and what it reveals about fasting myths [ 35:00 ] How GLP-1s may help food addiction by rewiring brain circuitry [ 39:45 ] Insights from four-year safety data: What we do and don\u2019t know about long-term use [ 42:00 ] Black box warnings and thyroid cancer risk\u2014what\u2019s real and what\u2019s hype? [ 44:50 ] Can someone taper off of GLP-1s successfully? Who are the 10\u201315% that do\u2014and how? [ 49:00 ] Will future GLP-1s render current meds obsolete? Why retatrutide may change the game [ 56:00 ] Super-responders vs. non-responders\u2014and the cortisol connection you\u2019ve never heard [ 59:00 ] Why Dr. DeFronzo thinks the next big breakthrough will be insulin-sensitizers [ 01:02:00 ] Final thoughts: a hopeful but cautionary note about access, cost and a new generation of GLP-1s on the way &amp;nbsp; ***  \ud83d\udd17 Mentioned in This Episode: Learn how to activate GLP-1 naturally and silence cravings! CLICK HERE TO GET \u21d2 Free Masterclass: Freedom From Food Noise: https:\/\/go.elizabethmcgann.com\/start &amp;nbsp; *** &amp;nbsp; Get Connected with Elizabeth McGann: Coaching Website: http:\/\/www.ElizabethMcGann.com Instagram:&amp;nbsp;http:\/\/www.instagram.com\/elizabethmcgann Facebook:&amp;nbsp;https:\/\/www.facebook.com\/ElizabethMcGannWellness LinkedIn:&amp;nbsp;https:\/\/www.linkedin.com\/in\/elizabethmcgann X\/Twitter:&amp;nbsp;https:\/\/twitter.com\/ElizabethMcGann &amp;nbsp; ***  Learn more about Dr. Ralph DeFronzo: University of Texas Health San Antonio Bio : https:\/\/directory.uthscsa.edu\/academics\/profile\/defronzo  Appearance on Dr. Peter Attia\u2019s THE DRIVE Podcast: https:\/\/www.youtube.com\/watch?v=vYQaLV3Fm00  Dr. DeFronzo\u2019s Work: Just Google him\u2014you\u2019ll find over 900 scientific publications! ","author_name":"The Holistic GLP-1 Podcast with Elizabeth McGann","author_url":"https:\/\/elizabethmcgann.com\/my-podcast\/","html":"<iframe title=\"Libsyn Player\" style=\"border: none\" src=\"\/\/html5-player.libsyn.com\/embed\/episode\/id\/37229285\/height\/90\/theme\/custom\/thumbnail\/yes\/direction\/forward\/render-playlist\/no\/custom-color\/88AA3C\/\" height=\"90\" width=\"600\" scrolling=\"no\"  allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen><\/iframe>","thumbnail_url":"https:\/\/assets.libsyn.com\/secure\/content\/190222325"}