{"version":1,"type":"rich","provider_name":"Libsyn","provider_url":"https:\/\/www.libsyn.com","height":90,"width":600,"title":"Ep. 6: Dr. Joshua Durham; Family Doc Gets Red-pilled by Seed Oils\u2014with Dr. Brian Kerley","description":"Dr. Durham is a Family Physician in Boise, Idaho; and is Tucker's doctor. We discuss how his practice has changed since he figured out how to solve his own chronic health problems, how this has changed his practice, some successes, and more. Joshua Durham, DO \u2022 https:\/\/www.saintalphonsus.org\/provider\/joshua-durham Blog comment: Dr. Durham: \u201cIf you need a family Dr. here in Boise hit me up. I went from 235lbs to keto to carnivore and then finally came across your info. Now at 195 I feel comfortable knowing what I can and can't have and why I was so sick. Felt great on carnivore but can't live that way forever. Thank you for your work.\u201d \u2022 http:\/\/yelling-stop.blogspot.com\/2021\/04\/experts-do-as-we-say-not-as-we-do.html?showComment=1620609617154#c416429453974276542 \u201cDoctor of Osteopathy vs. Medical Doctor- What are the Differences?\u201d \u2022 https:\/\/hecec.human.cornell.edu\/2016\/02\/12\/doctor-of-osteopathy-vs-medical-doctor-what-are-the-differences\/ Dr. Eric Westman \u2022 https:\/\/ericwestmanmd.com\/ New Atkins for a New You: The Ultimate Diet for Shedding Weight and Feeling Great by Eric C. Westman, Stephen D. Phinney, Jeff S. Volek \u2022 https:\/\/amzn.to\/3qd9fzy (this link benefits the podcast!) Dr. Durham: \u201cGood fat\/bad fat\u201d I wrote a post about this: \u201cGood Keto vs. Bad Keto\u201d \u2022 http:\/\/yelling-stop.blogspot.com\/2021\/09\/good-keto-vs-bad-keto.html Dr. Durham: \u201cThen I saw your interview with Paul Saladino\u2026\u201d \u2022 \u201cHow Seed Oils Destroy Your Mitochondria and Lead To Chronic Disease, with Tucker Goodrich\u201d https:\/\/carnivoremd.com\/how-seed-oils-destroy-your-mitochondria-and-lead-to-chronic-disease-with-tucker-goodrich\/ \u201c\u2026and then I watched Brad Marshall\u2026\u201d \u2022 Brad\u2019s blog is here: https:\/\/fireinabottle.net\/ Drs. Kerley and Durham compare \u201celevator pitches\u201d to patients. Dr. Durham: \u201cI needed 4 pills based on the guidelines, and I was 38 years old.\u201d Tucker: \u201cLean-Mass Hyper Responder\u201d: Norwitz, N. G., Soto-Mota, A., Kaplan, B., Ludwig, D. S., Budoff, M., Kontush, A., & Feldman, D. (2022). The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets. Metabolites, 12(5), 460. https:\/\/doi.org\/10.3390\/metabo12050460 Dr. Durham: 40:02 \u201cAmerican College of Cardiology article\u2026\u201d Astrup, A., Magkos, F., Bier, D. M., Brenna, J. T., de Oliveira Otto, M. C., Hill, J. O., King, J. C., Mente, A., Ordovas, J. M., Volek, J. S., Yusuf, S., & Krauss, R. M. (2020). Saturated Fats and Health: A Reassessment and Proposal for Food-based Recommendations: JACC State-of -the-Art Review. Journal of the American College of Cardiology, 76(7), 844\u2013857. https:\/\/doi.org\/10.1016\/j.jacc.2020.05.077 See Episode 5, in which we interview Tom Brenna, one of the co-authors of that article: https:\/\/www.youtube.com\/watch?v=rrQ8q_ctGUQ Tucker: \u201cThe AGEs, same thing\u2014Chris Masterjohn did a great post years ago looking into it: Masterjohn, C. (2011, October 7). Where Do Most AGEs Come From? O Glycation, How Thy Name Hast Deceived Me! | [Blog]. Chris Masterjohn, PhD. https:\/\/chrismasterjohnphd.com\/blog\/2011\/10\/07\/where-do-most-ages-come-from-o Tucker: \u201cPolyunsaturated fats are about 10x as effective in producing advanced glycation end products [than glucose]\u2026\u201d Fu, M.-X., Requena, J. R., Jenkins, A. J., Lyons, T. J., Baynes, J. W., & Thorpe, S. R. (1996). The Advanced Glycation End Product, N-(Carboxymethyl)lysine, Is a Product of both Lipid Peroxidation and Glycoxidation Reactions. Journal of Biological Chemistry, 271(17), 9982\u20139986. https:\/\/doi.org\/10.1074\/jbc.271.17.9982 Tucker: Lp(a): \u2022 Hazard ratio 16.8: Tsimikas, S., Brilakis, E. S., Miller, E. R., McConnell, J. P., Lennon, R. J., Kornman, K. S., Witztum, J. L., & Berger, P. B. (2005). Oxidized Phospholipids, Lp(a) Lipoprotein, and Coronary Artery Disease. New England Journal of Medicine, 353(1), 46\u201357. https:\/\/doi.org\/10.1056\/NEJMoa043175 \u2022 Hazard ratio 1 in Africa: Par\u00e9, G., \u00c7aku, A., McQueen, M., Anand, S. S., Enas, E., Clarke, R., Boffa, M. B., Koschinsky, M., Wang, X., Yusuf, S., & null,  null. (2019). Lipoprotein(a) Levels and the Risk of Myocardial Infarction Among 7 Ethnic Groups. Circulation, 139(12), 1472\u20131482. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.118.034311 \u2022 2 sure-fire ways to raise Lp(a): 1. Statins: Yeang, C., Hung, M.-Y., Byun, Y.-S., Clopton, P., Yang, X., Witztum, J. L., & Tsimikas, S. (2016). Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a). Journal of Clinical Lipidology, 10(3), 594\u2013603. https:\/\/doi.org\/10.1016\/j.jacl.2016.01.005 2. Healthy diet: Navab Mohamad, Reddy Srinivasa T., Van Lenten Brian J., & Fogelman Alan M. (2004). Apparent Paradox of Low-Fat \u201cHealthy\u201d Diets Increasing Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a). Arteriosclerosis, Thrombosis, and Vascular Biology, 24(3), 392\u2013393. https:\/\/doi.org\/10.1161\/01.ATV.0000118014.49565.fc \u2022 Pork and LDL: Stewart, J. W., Kaplan, M. L., & Beitz, D. C. (2001). Pork with a high content of polyunsaturated fatty acids lowers LDL cholesterol in women. The American Journal of Clinical Nutrition, 74(2), 179\u2013187. https:\/\/doi.org\/10.1093\/ajcn\/74.2.179 Treating Lp(a)\/OxLDL with antibodies: https:\/\/www.oxitopepharma.com\/approach Dr. Kerley: Robb Wolf interview: https:\/\/www.youtube.com\/watch?v=Lku8kJdHOqY Wooden breast in chickens: Soglia, F., Mudalal, S., Babini, E., Di Nunzio, M., Mazzoni, M., Sirri, F., Cavani, C., & Petracci, M. (2016). Histology, composition, and quality traits of chicken Pectoralis major muscle affected by wooden breast abnormality. Poultry Science, 95(3), 651\u2013659. https:\/\/doi.org\/10.3382\/ps\/pev353 \u201cDr. Mark Cucuzzella \u2013 A Doctor\u2019s Perspective On Treating Diabetes\u201d https:\/\/robbwolf.com\/2016\/07\/26\/episode-329-dr-mark-cucuzzella-a-doctors-perspective-on-treating-diabetes\/ ","author_name":"Tucker Goodrich: Debugging Life","author_url":"https:\/\/sites.libsyn.com\/408758","html":"