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  <title>Ep. 33: Brain Imaging of Chronic Pain with Anton Rogachov and Connor Wander</title>
  <description>This week we talked with Anton Rogachov, a 5th year PhD student in Dr. Karen Davis’s Lab at the University of Toronto. &amp;amp;nbsp;The Davis Lab focuses on using brain imaging like resting-state fMRI to understand functional abnormalities in the brains of chronic pain patients. &amp;amp;nbsp;The majority of Dr. Davis’s work looks at the functional communication between different brain regions and networks in order to understand how these&amp;amp;nbsp;communications break down in chronic pain. &amp;amp;nbsp;In comparison, Anton's research looks at regional brain oscillation and fluctuations an alternative approach to studying mechanistic brain function. Listen in to hear us discuss Anton's recent paper, Abnormal Low-Frequency Oscillations Reflect Trait-Like Pain Ratings in Chronic Pain Patients Revealed through a Machine Learning Approach.&amp;amp;nbsp; This research discovered that chronic pain patients do indeed have functional abnormalities in pain-related brain networks, but more importantly it showed that these abnormalities can be used to make inferences about the degree of pain the patients experience on a weekly basis. &amp;amp;nbsp;We cover what it's like to work directly with patients and to both administer and be tested via fMRI. &amp;amp;nbsp;We also talk about important caveats and considerations with work such as ours.  More information Read&amp;amp;nbsp;Anton’s recent paper on abnormal low-frequency oscillations Learn more in another publication by Anton on regional brain signal variability Check out a related episode on the molecular side of pain research,&amp;amp;nbsp;Ep. 30: Breaking the Vicious Cycle of Pain and Addiction with Waylin Yu. Listen to the Raw Talk Podcast run by scientists and medical students at the University of Toronto. Watch the&amp;amp;nbsp;TED Ed. video&amp;amp;nbsp;from Anton's supervisor Dr. Karen Davis on how your brain responds to pain. Thanks to Leigh at BrainPost for connecting us with Anton!  Any other questions?&amp;amp;nbsp;&amp;amp;nbsp;Let us know!&amp;amp;nbsp; We appreciate your feedback. You can now support the podcast at&amp;amp;nbsp;https://www.patreon.com/sfspodcast.&amp;amp;nbsp; Many thanks to our past and present supporters!&amp;amp;nbsp; Thanks to&amp;amp;nbsp;Plant Warrior&amp;amp;nbsp;for their support.&amp;amp;nbsp; Use discount code SFS10 at checkout for 10% off your purchase of plant-based protein.  </description>
  <author_name>The Straight from a Scientist Podcast</author_name>
  <author_url>https://www.straightfromascientist.com</author_url>
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