1 rich Libsyn https://www.libsyn.com 90 600 Recorded in Prato, Italy at the 8th Collaborative Clinical Trials in Anesthesiology meeting. Desiree Chappell and guest co-host Mark Priestley interview Professor Kariem El-Boghdadly, Consultant Anaesthetist and Clinical Lead for Theatres, Anaesthesia, and Peri-operative Medicine at Guy's and St Thomas' NHS Foundation Trust, as well as an Honorary Reader at King's College London about the perioperative implications of GLP-1 receptor agonists. El-Boghdadly explains expanding GLP-1 use, delayed gastric emptying, and why early “hold for a week” guidance may be impractical. He describes a UK trainee research network observational study across ~130 hospitals collecting ~47,000 cases, including ~1,300 GLP-1 patients, and reports an unadjusted ~11-fold higher aspiration/regurgitation rate in GLP-1 users (about 1 in 70) versus non-users (about 1 in 800), with about half occurring on emergence/extubation. The discussion emphasizes risk assessment, extubation planning, low uptake of gastric ultrasound, and the need for future randomized trials. The paper being discussed is here:&amp;nbsp;https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.70380 Checkout&amp;nbsp;EBPOM.org for more information and early bird tickets to our conferences now. TopMedTalk https://www.topmedtalk.com <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/43218563/height/90/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/3a5fa9/" height="90" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/content/207287098