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  <title>Dapagliflozin Before the Cardiac Surgery: Kidney Protection in Four Doses</title>
  <description>🫀💊 Can 4 doses help protect the kidney after cardiac surgery? MERCURI-2 randomized 784 patients to perioperative dapagliflozin or placebo. AKI within 7 days fell from 52% to 28%—RR 0.54, an absolute reduction of ~24% and NNT ≈4. 📉 Intriguingly, the signal was driven largely by urine-output–defined AKI; creatinine-only AKI was unchanged. Hard 30-day outcomes were also unchanged. 🎙️ A provocative new chapter in perioperative cardiorenal protection. 🛡️ </description>
  <author_name>Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity!</author_name>
  <author_url>http://www.MasterMedFacts.com</author_url>
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