In the Lab with Dr. Rashmi Mishra: Shapeshifting cancer into a more treatable form

1 rich Libsyn https://www.libsyn.com 90 600 In the Lab with Dr. Rashmi Mishra: Shapeshifting cancer into a more treatable form John Higgins interviews Dr. Rashmi Mishra, a postdoctoral research fellow in the Hsieh Lab at Fred Hutch Cancer Center, about how aggressive prostate cancer shapeshifts from a form that is treatable with drugs to a more lethal form that is much less treatable. In a recent study, she and her colleagues found potential ways to reverse that trick, forcing tumor cells to shapeshift back into the more treatable form. Their discovery opens a new line of attack against aggressive prostate cancer, as well as breast cancer and&nbsp;possibly other&nbsp;cancers.&nbsp; Key Takeaways:&nbsp; Prostate cancer&nbsp;comprises&nbsp;two main types of cells: luminal, which is more treatable with existing&nbsp;therapies&nbsp;and a more aggressive, lethal type called basal, which is much less treatable.&nbsp; A recent study by Dr. Rashmi Mishra, a postdoctoral research fellow in the Hsieh Lab at Fred Hutch Cancer Center, describes how prostate cancer shapeshifts from a luminal to a basal form to elude therapy without reprogramming its DNA.&nbsp; Mishra and her colleagues found potential ways to reverse that shapeshifting trick, forcing tumor cells to shapeshift back into the more treatable form.&nbsp; Their discovery opens a new line of attack against aggressive prostate cancer, as well as breast cancer and&nbsp;possibly other&nbsp;cancers.&nbsp; Bench to Bedside and Beyond https://sites.libsyn.com/591875 <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/42494205/height/90/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/88AA3C/" height="90" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/content/205255020