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  <title>In the Lab with Dr. Lucas Sullivan: let cancer eat cake</title>
  <description>Dr. Lucas Sullivan, a cancer metabolism expert at Fred Hutch Cancer Center talks with John Higgins about a new study showing that cancers driven by a specific mutation crave a nutrient so much that eating too much of it can be lethal. Healthy cells aren’t prone to stuffing themselves with this nutrient. That difference presents an opportunity for precision oncology: we can supplement a patient’s diet to force-feed tumors the nutrient while sparing healthy cells. &amp;amp;nbsp; Key takeaways:&amp;amp;nbsp;  A recent study by Dr. Lucas Sullivan, a cancer metabolism expert, finds that feeding NRF2-mutated tumors too much of a nutrient they crave makes them vulnerable to slower growth and cell death. NRF2 genetic mutations are common in lung cancers but also appear in several other cancers. Force-feeding NRF2-mutated tumors the nutrient they crave could kill the cancerous cells while sparing the healthy ones, a prime example of precision oncology.  </description>
  <author_name>Bench to Bedside and Beyond</author_name>
  <author_url>https://sites.libsyn.com/591875</author_url>
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