1 rich Libsyn https://www.libsyn.com 300 600 🧬 Can one rare gene reshape our approach to metabolic disease? A remarkable Nature study analyzing more than one million individuals identifies FNIP1 as a key regulator of energy metabolism. Rare loss-of-function variants were associated with healthier lipid profiles, lower liver fat, improved glycaemia, favorable fat distribution, and substantially lower cardiometabolic disease risk. Mechanistic studies in human hepatocytes and mice strengthen the biological story, making FNIP1 an exciting potential therapeutic target. A fascinating example of how human genetics can illuminate tomorrow’s treatments. 🚀🫀 #Nature #Genetics #Cardiology #Metabolism #PrecisionMedicine Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity! http://www.MasterMedFacts.com <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/42330080/height/300/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/88AA3C/" height="300" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/content/204815020