1 rich Libsyn https://www.libsyn.com 90 600 View the Show Notes For This Episode The Science of Longevity with Dr. Chris Renna | Rational Wellness Podcast 465 Longevity Medicine Deep Dive with Dr. Chris Renna: Lifestyle Foundations, Stem Cells, Regenokine &amp;amp; Rapamycin Dr. Ben Weitz welcomes longevity physician Dr. Chris Renna of Lifespan Medicine to discuss evidence-informed longevity and joint regeneration strategies. Renna argues that 90% of aging outcomes still come from diet, exercise (including resistance training), sleep, and psychological perspective, with supplements and hormones as important supports. He explains why stem cells are often overhyped, why many donor cells die quickly, and describes Muse cells as a type that can survive longer, noting Florida’s approval of umbilical cord cells for osteoarthritis and Lifespan’s plans to offer Muse cells. Renna outlines aging as incomplete daily repair beginning around age 30 and reviews Regenokine (autologous serum rich in anti-inflammatory factors/exosomes) as a top-performing joint injection without cartilage regrowth. He covers mitochondrial support, NAD precursors, urolithin A, peptides, and discusses low-dose intermittent rapamycin plus fisetin to reduce senescent cells, ending with a message of gratitude and presence. 00:00 Show Intro&amp;nbsp; 00:59 Meet Dr Chris Renna 02:17 Origins of Functional Medicine 03:42 Longevity Today and Tomorrow 05:49 Stem Cells Overhype 09:59 Why People Go Abroad 13:28 How Stem Cells Really Work 15:55 Muse Cells Explained 19:59 Aging Starts at 30 24:05 Joint Injection Breakthroughs 30:55 Regenokine and Exosomes 37:39 Diet and Food Quality 40:06 Clean Eating Basics 40:30 Hydration And Daily Movement 41:41 Sleep Skills And Wind Down&amp;nbsp; 43:31 Stress Perspective Reset 45:49 Core Supplements Stack&amp;nbsp; 47:23 Mitochondria Boosters 49:20 Peptides Hype And Risks 52:43 FDA Shifts And Hormones 57:21 Rapamycin Senescence Plan&amp;nbsp; 01:03:01 Longevity Vision And Wrap Up &amp;nbsp;Dr. Chris Renna is a physician and the founder of Lifespan Medicine, a practice focused on proactive, personalized approaches to health optimization and longevity. With over 30 years of clinical experience, Dr. Renna has been a pioneer in integrative and anti-aging medicine, emphasizing the interconnected roles of the immune, endocrine, and nervous systems in maintaining long-term health. His website is www.lifespanmedicine.com Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure. Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111. Rational Wellness Podcast https://www.drweitz.com <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/41592055/height/90/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/88AA3C/" height="90" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/content/202820500