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  <title>💉 One Shot, Lifelong LDL reduction? The Promise of Genomic Cardiology</title>
  <description>🧬 Could a single infusion replace decades of lipid-lowering therapy? &amp;amp;nbsp; The new NEJM study on VERVE-102 explores in vivo base editing of PCSK9 using CRISPR-inspired adenine base editing technology. In this phase 1 trial, a one-time infusion produced LDL cholesterol reductions up to 62% with durable effects extending beyond 1 year. ❤️ &amp;amp;nbsp; This may represent a major shift from chronic pharmacotherapy toward “once-and-done” genomic cardiovascular prevention. &amp;amp;nbsp; The science, safety, clinical implications, and future of gene-editing cardiology on “Dr RR Baliga’s Podkast for the Kurious Doc.” 🎙️🧠 &amp;amp;nbsp; #Cardiology #CRISPR #PCSK9 #PrecisionMedicine #Genomics #LDL #NEJM #MedicalInnovation #PreventiveCardiology #medicalpodca </description>
  <author_name>Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity!</author_name>
  <author_url>http://www.MasterMedFacts.com</author_url>
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