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IFM | Innovative Diagnostic Tools and Workflows for Suspected Alzheimer’s in Primary Care
In this special edition of Inside Family Medicine, sponsored by Roche Diagnostics, host Darren Sextro talks with brain health experts Deanna Willis, MD, MBA, a board-certified family physician, and Jared Brosch, MD, board-certified neurologist, on the use of blood-based biomarkers (BBBMs) in primary care settings for Alzheimer’s disease and related dementias. Their discussion explores how BBBMs can make referrals more efficient and enhance the evaluation of patients with cognitive decline. The conversation highlights the value of early diagnosis and therapy referrals as well as outlines effective workflow strategies for primary care teams.    This episode is brought to you by Roche Diagnostics.    Topics by Timestamp  00:00 Introduction  01:03 Meet the experts  02:22 Dr. Willis’ journey  04:32 Dr. Brosch’s journey  05:32 Connection between family medicine and neurology  07:24 New tools for early detection  11:19 Workflow models and biomarkers  14:08 Best practices for referrals  16:35 Biomarkers in practice  19:47 Conclusion and additional resources    Additional Resources:  Roche Diagnostics Elecsys Phospho-Tau (181P) Plasma decision summary  https://www.accessdata.fda.gov/cdrh_docs/reviews/K252163.pdf  2024 CEOi recommendations for clinical implementation of blood-based biomarkers for Alzheimer's disease: https://doi.org/10.1002/alz.14184  2025 Alzheimer’s Association clinical guidelines for primary care: https://doi.org/10.1002/alz.14333  Implementing early detection of cognitive impairment in primary care to improve care for older adults: https://doi.org/10.1111/joim.20098  FPM journal article: Blood Biomarkers and Early Detection of Alzheimer's Disease and Related Dementias  Brain health hub on AAFP.org including newest brain health resources  Brain health resources for patients from the AAFP    Disclaimer: Copyright 2026. AAFP. The views presented in this broadcast are the speaker’s own and do not represent those of AAFP. The information presented is for general, educational, or entertainment purposes and should not be considered legal, health, financial, or other advice.  AAFP makes no representation as to the accuracy or completeness of the information and is not responsible for results that may arise from its use.  Consult an appropriate professional concerning your specific situation and respective governing bodies for applicable laws. Reference to any specific product or entity does not constitute an endorsement or recommendation by AAFP unless specifically stated otherwise.  AAFP and the AAFP logo are registered trademarks of American Academy of Family Physicians.   
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