1 rich Libsyn https://www.libsyn.com 300 600 🧬 Tumours are not just masses of cells—they are organized ecosystems. &amp;nbsp; A remarkable Nature study by Zhang et al. mapped &amp;gt;10 million spatial transcriptomes across cancers and identified 9 conserved “spatial ecotypes” within the tumour microenvironment. Even more striking: these ecotypes could be detected non-invasively from plasma cell-free DNA using deep learning. &amp;nbsp; Higher SE7/SE8 predicted better immunotherapy outcomes, while SE4 forecast resistance and poorer survival. A powerful step toward blood-based spatial oncology and precision immunotherapy. 🚀🩸🔬 &amp;nbsp; Zhang W, Brown EL, Usmani A, et al. Nature. 2026. doi:10.1038/s41586-026-10452-4 Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity! http://www.MasterMedFacts.com <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/41197900/height/300/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/88AA3C/" height="300" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/content/201659355