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  <title> Lower LDL-C for Longer? Defining the Optimal Timing and Intensity of Rx</title>
  <description> Should&amp;amp;nbsp;statin therapy be routinely&amp;amp;nbsp;initiated&amp;amp;nbsp;in middle‑aged adults with at least one&amp;amp;nbsp;atherosclerotic cardiovascular disease&amp;amp;nbsp;risk factor and LDL‑C levels above&amp;amp;nbsp;100 mg/dL?&amp;amp;nbsp;Observational data consistently&amp;amp;nbsp;shows&amp;amp;nbsp;that lower LDL-C and non-HDL-C levels are associated with&amp;amp;nbsp;substantially reduced&amp;amp;nbsp;risks&amp;amp;nbsp;of atherosclerotic vascular disease. In the absence of randomized trial data in younger and middle-aged adults with low 10–30‑year risk, the role of&amp;amp;nbsp;additional&amp;amp;nbsp;risk stratification tools—such as&amp;amp;nbsp;hsCRP&amp;amp;nbsp;and coronary artery calcium scoring—becomes critical in guiding individualized decisions about when to begin lipid-lowering pharmacotherapy.&amp;amp;nbsp;   In this interview, William E. Boden MD, FACC&amp;amp;nbsp;and Roger&amp;amp;nbsp;S. Blumenthal, MD, FACC&amp;amp;nbsp;discuss ‘Lower LDL-C for Longer? Defining the Optimal Timing and Intensity of&amp;amp;nbsp;Rx’.&amp;amp;nbsp;  </description>
  <author_name>ACCEL Lite: Featured ACCEL Interviews on Exciting CV Research</author_name>
  <author_url>http://accelaccorg.libsyn.com/website</author_url>
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