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  <title>Exploring the Obesity-Cancer Connection: A Pioneering Research Initiative</title>
  <description>In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by Dr. Kristy Brown and Dr. John Jakicic, co-leaders of KU Cancer Center’s new Obesity, Metabolic Health &amp;amp;amp; Cancer research program, the first of its kind at an NCI-designated cancer center focused on the obesity–cancer link. They discuss rising obesity rates, obesity’s link to at least 13 cancers, and key biological mechanisms including insulin and glucose signaling, inflammation, and hormone changes such as estrogen. The guests explain how this new program will harmonize cancer and obesity research, study how changes in adiposity and tissue quality affect cancer risk and treatment response, and develop interdisciplinary, community-informed prevention and intervention strategies, including lifestyle approaches and newer obesity medications, to improve outcomes and survivorship. 00:00 Obesity and Cancer Link 01:03 Why KU Cancer Center Launched Program 03:47 How Obesity Fuels Cancer 05:57 Reversing Risk Questions 07:10 First of Its Kind Program 09:30 Obesity as the New Tobacco 10:35 Team Science and Partnerships 13:10 Patient Impact and Trials 16:46 Tissue Quality and Muscle 18:52 Next Decade Opportunities 21:31 Equity and Real-World Barriers 22:12 Evidence and Expert Validation 24:25 Closing and Resources Links from this Episode:  ·&amp;amp;nbsp;&amp;amp;nbsp;&amp;amp;nbsp;&amp;amp;nbsp;&amp;amp;nbsp;&amp;amp;nbsp; Learn more about the new Obesity, Metabolic Health &amp;amp;amp; Cancer Research Program at KU Cancer Center To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center. </description>
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