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E.203 PEPTIDE PLAYBOOK – PART 3 Hormones, Testosterone & the Future of Longevity Medicine
In this episode of the Peptide Playbook Series, Dr. Din sits down with Dr. Frankel to discuss the science behind testosterone, hormone replacement therapy, peptides, and metabolic health. As we age, many people experience fatigue, weight gain, brain fog, and metabolic changes. According to Dr. Frankel, three major factors often drive these changes: hormone deficiency, insulin resistance, and energy deficiency in the body. In this conversation, we break down how testosterone interacts with estrogen, why self-treating with supplements like DHEA can be misleading, and how therapies such as GLP-1 peptides, NAD, and growth hormone peptides may help restore metabolic balance. We also discuss the differences between menopause, andropause, and the often overlooked “somatopause” — the age-related decline in growth hormone. Topics include: • Testosterone therapy for men and women • Hormone replacement and metabolic health  • Cholesterol and hormone production • GLP-1 peptides and insulin sensitivity • Peptides used in longevity medicine  • The connection between hormones and aging Part of the Peptide Playbook Series, exploring the science behind peptides, metabolism, and modern longevity medicine.  🔗 CONNECT WITH DR. SOFIA DIN 📸 Instagram   / drjuvanni   🎙️ Apple Podcasts – Bathroom Diaries https://podcasts.apple.com/za/podcast... 🎧 Spotify – Bathroom Diaries https://open.spotify.com/show/7sNfitf... 🔗 CONNECT WITH DR. ROB FRANKEL 📸 Instagram   / vitale_wellnessclub   ▶️ YouTube    / @simply.aestheticsmedspa2293      00:00 Intro & Welcome Back 01:10 Why Hormone Health Is Misunderstood  03:30 The Gap in Medical Training (Hormones & Nutrition)  05:45 Testosterone Basics Explained 08:20 Aging in Men: Testosterone Decline & Estrogen Rise  11:00 The Truth About DHEA Supplements 14:10 Why Self-Treating Hormones Can Backfire 17:30 Symptoms of Low Testosterone in Men  20:15 Cholesterol’s Role in Hormone Production 23:40 Statins & Their Impact on Hormones  27:10 Low Testosterone & Metabolic Disease Risks 31:00 Insulin Resistance, Inflammation & Chronic Disease  34:20 How to Properly Start Hormone Optimization  38:10 Foundation Protocol: Hormones, NAD, GLP-1 42:00 Testosterone Therapy: Dosing & Approach 45:20 Testosterone in Women: Benefits & Myths  48:30 Estrogen Dominance & Cancer Risk 51:10 Who Should NOT Take Testosterone?  53:40 Testosterone & Prostate Cancer Myth Debunked 57:10 Real Study Insights (2019 Shift in Perspective)  59:10 Final Takeaways on Hormones & Longevity  01:00:20 Outro & Next Episode Preview (Somatopause)
Bathroom Diaries w. Dr Sofia Din
https://botoxguru.org/
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