1 rich Libsyn https://www.libsyn.com 90 600 In this episode of the Innovations and Clinical Implementation podcast, hosts Dr. Lexi Gonzales and Tom Blue interview Dr. Sundeep Dugar, a pharmaceutical drug hunter with nearly 40 years of experience in small molecule discovery who serves as the co-founder and Chief Scientific Officer at Blue Oak Nutraceuticals. The conversation focuses on the development of Mitocatalyst, a precision-formulated epicatechin designed to mimic the mitochondrial biogenesis normally triggered by exercise. Dr. Dugar reveals his breakthrough discovery that exercise-induced Reactive Oxygen Species (ROS) signal the mitochondria to produce a specific steroid—11-beta hydroxyprogesterone—and explains how Mitocatalyst utilizes nanomolar doses of epicatechin to molecularly mimic this steroid, distinguishing it from high-dose antioxidant protocols that paradoxically blunt these beneficial signals. The discussion uses the metaphor of building a &quot;fireplace&quot; (mitochondria) to burn &quot;firewood&quot; (nutrition), positioning the supplement as a critical intervention for aging patients or those unable to exercise. For access to episode resources: https://sites.google.com/ovationlab.com/innovationsinclinicalimplement/home Redefining Medicine https://www.a4m.com/redefining-medicine-podcast.html <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/39929830/height/90/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/5bc6cc/" height="90" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/content/198031155