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  <title>#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore</title>
  <description>Today, I’m joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators. &amp;amp;nbsp; Use code NAT10 for 10% off products at https://alchemiqlabs.com/ &amp;amp;nbsp; Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore’s path from strength coaching to cellular&amp;amp;nbsp;medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02 &amp;amp;nbsp; Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off. &amp;amp;nbsp; BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20. &amp;amp;nbsp; Complete Liver Complex by LVLUP Health - supports your liver’s natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off. &amp;amp;nbsp; Nat's Links:&amp;amp;nbsp; YouTube Channel Join My Membership Community Sign up for My Newsletter&amp;amp;nbsp; Instagram&amp;amp;nbsp; Facebook Group </description>
  <author_name>LONGEVITY with Nathalie Niddam</author_name>
  <author_url>https://www.nathalieniddam.com/</author_url>
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