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  <title>Top Takeaways from 2025: EP with DJ Lakkireddy, MBBS, FACC</title>
  <description> In this interview, DJ&amp;amp;nbsp;Lakkireddy, MBBS, FACC and Alison L. Bailey, MD FACC, discuss the Top Electrophysiology Takeaways from 2025 including trials CLOSURE-AF, ALONE-AF, NEMESIS-PFA, and more.&amp;amp;nbsp;   &amp;amp;nbsp;Suggested Materials:&amp;amp;nbsp;   1. Verma A, Birnie DH, Jiang C, et al. Antithrombotic Therapy after Successful Catheter Ablation for Atrial Fibrillation.&amp;amp;nbsp;N Engl J Med. Published online November 8, 2025. doi:10.1056/NEJMoa2509688&amp;amp;nbsp;&amp;amp;nbsp;&amp;amp;nbsp;   2. Landmesser U, Skurk C, Kirchhof P, et al.&amp;amp;nbsp;Catheter-based left atrial appendage CLOSURE in patients with atrial fibrillation at&amp;amp;nbsp;high risk&amp;amp;nbsp;of stroke and bleeding as compared to best medical therapy: Rationale and design of the prospective randomized CLOSURE-AF trial. Am Heart J. Published online September 12, 2025.&amp;amp;nbsp;doi:10.1016/j.ahj.2025.09.005&amp;amp;nbsp;&amp;amp;nbsp;   3. Kim D, Shim J, Choi EK, et al.&amp;amp;nbsp;Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation: The ALONE-AF Randomized Clinical Trial.&amp;amp;nbsp;JAMA. 2025;334(14):1246-1254.&amp;amp;nbsp;doi:10.1001/jama.2025.14679&amp;amp;nbsp;&amp;amp;nbsp;&amp;amp;nbsp;   4.&amp;amp;nbsp;Lakkireddy&amp;amp;nbsp;D,&amp;amp;nbsp;Katapadi&amp;amp;nbsp;A,&amp;amp;nbsp;Garg&amp;amp;nbsp;J, et al.&amp;amp;nbsp;NEMESIS-PFA: Investigating Collateral Tissue Injury Associated&amp;amp;nbsp;With&amp;amp;nbsp;Pulsed Field Ablation. JACC Clin&amp;amp;nbsp;Electrophysiol. 2025;11(8):1747-1756.&amp;amp;nbsp;doi:10.1016/j.jacep.2025.04.017&amp;amp;nbsp;&amp;amp;nbsp;&amp;amp;nbsp;   5.&amp;amp;nbsp;Wazni&amp;amp;nbsp;OM, Saliba WI, Nair DG, et al.&amp;amp;nbsp;Left Atrial Appendage Closure after Ablation for Atrial Fibrillation. N&amp;amp;nbsp;Engl&amp;amp;nbsp;J Med. 2025;392(13):1277-1287. doi:10.1056/NEJMoa2408308&amp;amp;nbsp;   &amp;amp;nbsp;Subscribe on Apple&amp;amp;nbsp;Podcasts&amp;amp;nbsp;|&amp;amp;nbsp;Subscribe to ACCEL&amp;amp;nbsp;  </description>
  <author_name>ACCEL Lite: Featured ACCEL Interviews on Exciting CV Research</author_name>
  <author_url>http://accelaccorg.libsyn.com/website</author_url>
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