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  <title>CAR T-cell therapy with Dr. Mazyar Shadman</title>
  <description> Dr.&amp;amp;nbsp;Mazyar&amp;amp;nbsp;Shadman is a blood cancer specialist at Fred Hutch Cancer Center who focuses on lymphoid malignancies. In a conversation with Bonnie Rochman, they explore the advancements in CAR T-cell therapy, particularly for large B-cell lymphoma, highlighting its impact on patient outcomes and survival rates.&amp;amp;nbsp;   Takeaways&amp;amp;nbsp;     CAR T therapy is a significant advancement in cancer treatment. The future of cancer treatment may heavily rely on CAR T advancements.&amp;amp;nbsp; CAR T therapy represents&amp;amp;nbsp;a shift in cancer care paradigms. It is particularly effective for large B-cell lymphoma. Patients with relapsed disease historically had limited survival chances. CAR T therapy has improved outcomes for high-risk patients. 30 to 40% of patients are now being cured with CAR T therapy. The treatment offers  better&amp;amp;nbsp;quality of life compared to standard care. Ongoing research is crucial for further advancements in CAR T. Patient selection is key  for&amp;amp;nbsp;the success of CAR T therapy.    </description>
  <author_name>From Bench to Bedside and Beyond</author_name>
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