1 rich Libsyn https://www.libsyn.com 90 600 Cindy and Steph discuss a paper that challenges the textbook dogma that B cells must first bind to an antigen for antibody affinity maturation to occur, and a snippet on dysfunctional T cells during bacterial vaginosis. Hosts:&amp;nbsp;Cindy Leifer&amp;nbsp;and&amp;nbsp;Steph Langel Subscribe (free): Apple Podcasts,&amp;nbsp;RSS,&amp;nbsp;email Become a&amp;nbsp;patron&amp;nbsp;of&amp;nbsp;Immune! Links for this episode MicrobeTV Discord Server Somatic&amp;nbsp;hypermutation in non-specific&amp;nbsp;B cells (Immunity 2025) Dysfunctional&amp;nbsp;T cells during bacterial&amp;nbsp;vaginosis (J Clin Invest 2025) Time stamps by&amp;nbsp;Jolene&amp;nbsp;Ramsey. Thanks! Music by Tatami. Immune logo image by&amp;nbsp;Blausen Medical Send your immunology questions and comments to&amp;nbsp;immune@microbe.tv Information on this podcast should not be construed as medical advice. Immune http://microbe.tv/immune <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/38526480/height/90/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/88AA3C/" height="90" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/item/38526480