1 rich Libsyn https://www.libsyn.com 300 600 🔬 Exciting new insights from Nature (2025)! When mitochondria run low on the right building blocks (deoxyribonucleotides), they mistakenly weave ribonucleotides into their DNA 🧬. The result? Fragile mitochondrial DNA gets expelled, setting off the cGAS–STING pathway and fueling inflammation 🔥—a key feature of ageing and senescence. &amp;nbsp; 🧪 In MGME1-deficient mice, this process drives renal inflammation, while supplementation with deoxyribonucleosides 💊 can calm the storm. &amp;nbsp; ✨ A major step in understanding “inflammageing” and potential interventions for age-related diseases. &amp;nbsp; #Mitochondria #DNA #Ageing #Inflammation #NaturePaper Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity! http://www.MasterMedFacts.com <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/38408390/height/300/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/88AA3C/" height="300" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/content/193617855