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  <title>Oncometabolites and The Heart</title>
  <description>Oncometabolites and The Heart Dr RR Baliga 'Got Knowledge Doc' PodKasts for Cardio-Oncologists  Baliga RR, Young JB. Energizing Diastole Heart Fail Clin. 2008;4(1):ix‐xiii.  Energizing Diastole Sulkowski, P.L., Oeck, S., Dow, J. et al. Oncometabolites suppress DNA repair by disrupting local chromatin signalling. Nature (2020).   Tumour metabolites hinder DNA repair  &amp;amp;nbsp;   Krebs Cycle Nobel Lecture  &amp;amp;nbsp;   Ivosidenib and Cardiogenic Shock  &amp;amp;nbsp;   Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart. Proc Natl Acad Sci U S A.  &amp;amp;nbsp;  &amp;amp;nbsp;D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice. Genes Dev.  &amp;amp;nbsp;   Changes in Citric Acid Cycle and Nucleoside Metabolism Are Associated with Anthracycline Cardiotoxicity in Patients with Breast Cancer. J Cardiovasc Transl Res.  &amp;amp;nbsp;  Krebs Cycle Primer Khan Academy   Taegtmeyer H, et al&amp;amp;nbsp; Oncometabolic Tracks in the Heart. Circ Res. 2017 &amp;amp;nbsp; &amp;amp;nbsp; &amp;amp;nbsp; </description>
  <author_name>Dr. RR Baliga's 'Podkast for the Kurious Doc'. Where Curiosity meets Clarity!</author_name>
  <author_url>http://www.MasterMedFacts.com</author_url>
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