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  <title>The Therapycast Vol 2 No 8</title>
  <description>In this podcast I explore some of the latest ideas regarding depression and share a fellow podcasters experience of living with and being treated for depression. Music A Strong Will is Needed by Derek Clegg  http://freemusicarchive.org/search/?quicksearch=a+strong+will+is+needed DumTeeDum Podcast Dum Tee Dum can be found on iTunes:  https://podcasts.apple.com/gb/podcast/dumteedum-a-show-about-the-bbcs-the-archers/id858767884 Their website is www.dumteedum.com Detecting risk of depression Halldorsdottir, T., Piechaczek, C., Soares de Matos, A. P., Czamara, D., Pehl, V., Wagenbuechler, P., ... &amp;amp;amp; Greimel, E. (2019). Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths.&amp;amp;nbsp;American Journal of Psychiatry, appi-ajp. Brain Insulin Resistance and Depression  Bădescu S, Tătaru C, Kobylinska L, et al.The association between diabetes mellitus and depression.&amp;amp;nbsp;J Med Life. 2016;9(2):120-125. Hamer J, Testani D, Mansur R, Lee Y, Subramaniapillai M, McIntyre R.Brain insulin resistance: a treatment target for cognitive impairment and anhedonia in depression.&amp;amp;nbsp;Exp Neurol. 2019;315:1-8. Lyra e Silva NM, Lam MP, Soares CN, Munoz DP, Milev R, De Felice FG.Insulin resistance as a shared pathogenic mechanism between depression and type 2 diabetes.&amp;amp;nbsp;Front Psychiatry. 2019;10:57. Arnold SE, Arvanitakis Z, Macauley-Rambach SL.Brain insulin resistance in type 2 diabetes and alzheimer disease: concepts and conundrums.&amp;amp;nbsp;Nat Rev Neurol. 2018;14(3):168-181. Sripetchwandee J, Chattipakorn N, Chattipakorn SC.Links between obesity-induced brain insulin resistance, brain mitochondrial dysfunction, and dementia.&amp;amp;nbsp;Front Endocrin (Lausanne).2018;9:496. Kullmann S, Heni M, Hallschmid M, Fritsche A, Preissl H, Häring HU.Brain insulin resistance at the crossroads of metabolic and cognitive disorders in humans.&amp;amp;nbsp;Physiol Rev. 2016;96(4):1169-1209. Singh MK, Leslie SM, Packer MM.Brain and behavioral correlates of insulin resistance in youth with depression and obesity.&amp;amp;nbsp;Horm Behav. 2019;108:73-83.&amp;amp;nbsp;  Meta Analysis for Depression and Hypnosis Milling, L. S., Valentine, K. E., McCarley, H. S., &amp;amp;amp; LoStimolo, L. M. (2018). A Meta-Analysis of Hypnotic Interventions for Depression Symptoms: High Hopes for Hypnosis?.&amp;amp;nbsp;American Journal of Clinical Hypnosis,&amp;amp;nbsp;61(3), 227-243. </description>
  <author_name>The Therapycast</author_name>
  <author_url>http://www.petermabbutt.net</author_url>
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