1 rich Libsyn https://www.libsyn.com 300 600 Tumor cells WASH away the extracellular matrix Tumor cells invade through extracellular matrices by forming actin-rich structures called invadopodia, which contain the transmembrane matrix metalloproteinase MT1-MMP.&amp;nbsp;Monteiro et al.&amp;nbsp;reveal that the Arp2/3 activating protein WASH works with the exocyst complex to deliver MT1-MMP from late endosomes to the invadopodial plasma membrane. This biosights episode presents the paper by&amp;nbsp;Monteiro et al.&amp;nbsp;from the December 23, 2013, issue of&amp;nbsp;The Journal of Cell Biology&amp;nbsp;and includes an interview with senior author Philippe Chavrier (Institut Curie, Paris, France). Produced by Caitlin Sedwick and Ben Short. See the associated paper in&amp;nbsp;JCB&amp;nbsp;for details on the funding provided to support this original research. Subscribe to biosights via&amp;nbsp;iTunes&amp;nbsp;or&amp;nbsp;RSS View&amp;nbsp;biosights archive The Rockefeller University Press biosights@rockefeller.edu biosights http://www.jcb.org/biosights <iframe title="Libsyn Player" style="border: none" src="//html5-player.libsyn.com/embed/episode/id/5957281/height/300/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/88AA3C/" height="300" width="600" scrolling="no" allowfullscreen webkitallowfullscreen mozallowfullscreen oallowfullscreen msallowfullscreen></iframe> https://assets.libsyn.com/secure/item/5957281